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Can Stroke Physicians and Neuroradiologists Identify Signs of Early Cerebral Infarction on CT? JNNP 67:651-653, Wardlaw,J.M.,et al, 1999 See this aricle in Pubmed Article Abstract Only 65% of the CT scans from 14 stroke patients were correctly identified as normal or abnormal (95% CI 60-69%). Neither observer experience nor knowledge of symptoms significantly improved recognition of abnormality, although experience did significantly improve the observers' ability to reproduce their results. Parenchymal hypodensity was the least well recognised sign. Only 45% (95% CI 40-50%) of patients were identified correctly for the hypothetical acute stroke treatment trial. E arly infarction on CT is not well recognised even by experienced doctors. Part of the problem may be in understanding the definitions of the extent of infarction. These difficulties should be considered in the design of acute stroke treatment trials and in the introduction of any new acute stroke treatments.

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